The Nebraska Public Health Lab will confirm all presumed carbapenemase-producing CRE isolates detected in Nebraska laboratories. Antimicrobial resistance is a serious threat to public health across the globe. FDA is also implementing the Generating Antimicrobial Incentives Now (GAIN) Act provisions of the Food and Drug Administration Safety and Innovation Act (FDASIA) to help facilitate antibacterial drug development. The department will measure impact by the improvement of cluster response and disease rates. AASV will advocate for science-based approaches to veterinary, industry, and public health issues, including antimicrobial resistance. Pollution from inadequate treatment of industrial, residential, and farm waste is expanding the resistome in the environment. Oklahoma State Department of Health (OSDH) commits to expanding capacity to detect, prevent, and respond to antibiotic resistance in rural and urban medical facilities by educating healthcare staff through six statewide trainings on the key components of antibiotic resistance and stewardship by the end of December 2019. Revisions will reflect findings by the Task Force on Antimicrobial Stewardship in Companion Animal Practice and the American Veterinary Medical Association Committee on Antimicrobials. ImmunoBiology Limiteda technology company in the United Kingdom developing vaccines for infectious diseasescommits to developing a universal multi-protein pneumococcal vaccine for global use to fight against antibiotic resistance. Pediatric Infectious Disease Society (Virginia, U.S.) SCYNEXIS is committing to initiate studies of this antifungal in the treatment of patients with Invasive Aspergillosis and patients with fungal infections that are resistant to current therapies, including patients with Candida auris. The aminoglycosides are a class of antibiotics that mainly act on Gram-negative . Ohio State University Wexner Medical Center commits to developing an Antibiotic Time Out (ATO) program to promote consistent review of the appropriateness of antibiotic prescribing for its patients to combat antibiotic resistance. SpeeDx, a diagnostic manufacturer, commits to developing novel diagnostic tools that go beyond detection, providing therapeutic guidance to clinicians for improved patient care and antimicrobial stewardship. length of stay) Ref:17, Antibiotics in primary care Pharmaceutical Benefit Scheme (PBS) In 2015, around half of the Australian population had at least one antimicrobial dispensed under the PBS (44.7% n = 10,701,804) Ref:18, Antibiotics in primary care NPS MedicineWise Medicine Insight In 2015, only 23.5% of patients prescribed antimicrobials had an indication recorded Of these people, 60% who were reported to have colds/upper respiratory tract infections were prescribed an antimicrobial But antimicrobials are not generally recommended for these conditions, Understanding Variation Variation raises concerns about equity and safety and appropriateness of care There is marked variation in use of antibiotics between states between hospitals different sizes within the same size The reasons for this are not well understood Also marked variation in community dispensing of antibiotics The first Australian Atlas of Healthcare Variation (2015) included information on community antibiotic use The third Atlas will be released later this year containing antibiotic data at a national level Further data will be available at state and territory level in 2019, Number of PBS prescriptions dispensed for amoxicillin-clavulanate per 100,000 people, agestandardised, by local area, 201314 Ref:19, Antimicrobial Stewardship (AMS) Antimicrobial Stewardship isnt about not using antimicrobials but rather identify that small group of patients who really need antibiotic treatment and then explain, reassure and educate the large group of patients who dont Stewardship means to protect something AMS is a systematic approach to optimising the use of antimicrobials Goals of AMS are to: improve patient outcomes / patient safety reduce antimicrobial resistance reduce costs. The medical center program will decrease unnecessary broad-spectrum antibiotic use by prompting review and evaluation of antibiotic use after 48 hours (antibiotic time-out), enhanced stewardship activities, and infection prevention efforts focused on preventing hospital-acquired infections. Alliance companies are committed to contribute to and measure their efforts in fighting AMR across four key areas: research, appropriate use, access, and manufacturing and the environment. In 2019, the collaborative will host a convening involving key stakeholders from the plumbing industry, governments, non-government organizations, and multilateral institutions in a targeted session on WASH in healthcare facilities. Mississippi State Department of Health (Mississippi, U.S.) Sackler Institute for Nutrition Science (New York, U.S.) The 5D Health Protection Group Ltd commits to developing new antimicrobial and antibiofilm agents by 2022. ASCP commits to promoting antibiotic stewardship across the spectrum of older adult care through practice resource development, industry partnerships, educational materials, and proactive market research and support. Accessibility Prescribing for Upper Respiratory Tract Infection (URTI) Marked seasonal variation in agents used for RTI Significant amount of antibiotics prescribed for respiratory tract infections (RTI) Seasonal variation is driven by viruses which do not respond to antibiotics Data shows that 60% of patients who present with RTI will be prescribed antibiotics. Premier, a healthcare improvement company with a network of approximately 4,000 U.S. hospitals and health systems and approximately 165,000 other providers and organizations, is committed to continue to reduce preventable harms caused by hospital-acquired infections and inappropriate antimicrobial use. The Washington State Department of Health commits to addressing the threat of antibiotic resistance through the Combating Antibiotic Resistant Bacteria Initiative to stop the emergence and transmission of antibiotic-resistant organisms. AAOS will also increase awareness of when antibiotics should and should not be used for patients with hip and knee implants who are undergoing dental procedures. The Georgia Department of Public Health (GDPH) commits to using survey data from 350 dentists in the state to improve antibiotic use in dental settings. Other antibiotics are active on both types of bacteria >> Broad spectrum antibiotics. HCA Healthcare (Tennessee, U.S.) HHS Vulnerability Disclosure, Help The Colorado Department of Public Health and Environment (CDPHE) commits to addressing the threat of antibiotic resistance by creating a comprehensive state report that will be publicly available on the CDPHE website by December 2, 2019. U.S. Centers for Disease Control and Prevention (Georgia, U.S.) Without action to tackle this, experts predict that resistance will continue to spread until most antibiotics stop working. Working with the Washington State Department of Health, UW TASP will adopt and develop web-ready guidelines and practical toolkits to promote appropriate antibiotic use and reduce infections caused by drug-resistant germs. ConvenientMD anticipates improving provider satisfaction by supplying evidence-based guidelines and patient education materials. CDC Foundation (Georgia, U.S.) The hospitals Antimicrobial Stewardship Program Committee and the Infection Prevention Committee will work hand-in-hand to reduce inappropriate use of antibiotics and adverse events, as well as increase infection prevention interventions such as vaccination initiatives and averting hospital-acquired infections. This commitment includes working with care delivery transformation teams who interact directly with physicians to improve member education. By continuing work with CDC on their pilot and working with public health labs in the U.S. and worldwide, HP hopes to enable rapid reference method testing of new antibiotics for resistant infections. the antibiotic resistance, NEVADANS FOR ANTIBIOTIC AWARENESS - The antibiotic resistance crisis. It was soon discovered however, that the microorganisms were capable of developing resistance to any of the drugs that were used. Additionally, NYSDOH is analyzing Medicaid data to identify high prescribing areas in the state, and to improve outpatient antibiotic prescribing. Society for Pediatric Urgent Care (Virginia, U.S.) Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Summit Therapeutics is committed to discovering and developing new antibiotics for serious infectious diseases. Do you have access to a local antibiogram? These products can help healthcare providers better and more rapidly treat patients with resistant infections and stop the spread of resistant germs, like carbapenem-resistant Enterobacterales. In order to reduce the mortality or disability caused by by C. auris, Los Angeles Biomedical Research Institute at Harbor/UCLA (LABiomed), in collaboration with NovaDigm Therapeutics, Inc., commits to the development of a vaccine for by C. aurisin order to prevent the spread of infections and save lives. The initiative will promote oral care and bathing, hand hygiene, and bundle compliant device maintenance. Resistance to antimicrobial agents has become a major source of morbidity and mortality worldwide. As part of this, Argonne is collaborating with CDC on better predicting resistance in Clostridioides difficile. WaterAid is focused on WASH as a fundamental and primary preventative measure to reduce the occurrence and spread of infections that lead to use, misuse, and overuse of antibiotics and that can drive resistance. Hy-Plains has conducted vaccine, feed additive, antibiotic treatment, immune response, and retrospective data analysis trials and commits to working with partners to bring the results of its research to scale throughout the industry in a more rapid manner. The Nevada Division of Public and Behavioral Health commits to addressing the threat of antibiotic resistance through its Healthcare-Associated Infection (HAI) Program. PipelineRx created a cloud-based integration platform that pulls data directly from electronic health records (EHR) and sends it to CDCs National Healthcare Safety Network for upload into the Antimicrobial Use and Resistance (AUR) modules. Its Antibiotic Stewardship Collaborative helps healthcare organizations improve their antibiotic stewardship efforts and prepare for anticipated mandates. The Company is currently developing antibiotics for C. difficile, gonorrhea and ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species). Medline Industries, Inc.manufacturer and distributor of medical products in more than 90 countriescommits to raising awareness of antibiotic resistance and combating emerging pathogens by supporting research and development aimed at reducing the spread of resistant pathogens. In particular, Abt Associates aims to help better understand the status and threat of antibiotic resistance among private health facilities and pharmacies worldwide, among formal and informal providers, and to collect data on contextual factors that contribute to antibiotic resistance in particular geographic regions. Antimicrob Resist Infect Control. What AMS activities are you / your department involved in? Government of Japan (Japan) SpeeDx is collaborating with researchers, clinicians, organizations and industry partners as part of a Transformational Research Hub, funded by the Australian government, to address the increase of antimicrobial resistance. The VA is also working with CDC to scale-up stewardship interventions in VA outpatient and acute care settings, and to refine methods for measuring hospital antibiotic use in the National Healthcare Safety Network. Alaska Department of Health and Social Services (Alaska, U.S.) Velox Biosystems, a clinical diagnostics startup out of University of California Irvine, is committed to applying their innovative detection technology to develop rapid, cost effective, and highly accurate tests and instruments to combat the rise of antibiotic resistance. Antimicrobial resistance (AMR) is a growing problem in the 21 st century and one of the most serious jeopardies to global public health . Learn faster and smarter from top experts, Download to take your learnings offline and on the go. The University of North Carolina Medical Centers Antimicrobial Stewardship and Infection Prevention Program commits to reducing the risk of antimicrobial resistance and C. difficile infections in its hospitals. A second visit with WHO principles was hosted in March 2018 to introduce new WHO leadership on AMR to HHS and U.S. Department of Agriculture principles. The University of Washington Tele-Antimicrobial Stewardship Program (UW TASP) commits to working with Critical Access Hospitals and rural hospitals across the Pacific Northwest to reduce inappropriate antibiotic use via education, empowerment, and best practices. FAIRR is a global network of institutional investors focused on building a sustainable food system that is supported by more than 200 investors representing $12 trillion in combined assets. VDH also commits to collaborating with partner organizations in the Virginia Healthcare-Associated Infections Advisory Group to offer trainings to healthcare providers across practice settings. Serving as a technical partner to ministries of health, it develops, finances, and implements their national programs for the strengthening of emergency and essential surgical care and anesthesia. 2. Henry Ford Health System (Michigan, U.S.) Most of the classes of antimicrobials used to treat bacterial infections in humans are also used in animals. Engineering Ministries International (EMI), a Christian non-profit development organization of architects, engineers, surveyors, and construction managers, commits to being a technical resource for the design and implementation of appropriate and sustainable safe drinking water, sanitation, and hygiene (WASH) solutions in the healthcare facilities and communities where they work. CHAGs role as key champions, pioneers, and advocates of WASH will be a priority commitment until all CHAG facilities become fully WASH compliant by the year 2030. ImmunoBiology Limited (United Kingdom) NIPH commits to continue to work internationally through organizations such as the Transatlantic Taskforce on Antimicrobial Resistance and the European Unions Joint Action on AMR and healthcare-associated infections to engage healthcare providers to improve stewardship measures as well as find common ground to implement mechanisms that can further stimulate necessary research and innovation. International Association of Plumbing and Mechanical Officials and LIXIL Americas (California, U.S.) New Mexico Department of Health, Epidemiology and Response Division (New Mexico, U.S.) AMR - Happens when microorganisms change when they are exposed to antimicrobial drugs "superbugs" - Microorganisms that develop antimicrobial resistance As a result, Medicines become ineffective Infections persist in the body Increasing the risk of spread to others. SHARPS will increase the number of SHARPS Collaborative hospitals conducting antimicrobial stewardship at time of discharge by 50% and the number of its hospitals submitting pediatric specific data by 50%. Biotia, an artificial intelligence, health tech firm, commits to advancing available technology such as sequencing-based laboratory workflow, software, and databases to help quickly and accurately identify and track antimicrobial resistance in healthcare settings. Pew Charitable Trusts (Pennsylvania, U.S.) The Wyoming Department of Health commits to promoting the appropriate use of antibiotics and vaccinations in hospitals and nursing homes. CHAG further commits to integrate WASH in all services it provides, including health training schools. 3 4. The International Consortium for Antimicrobial Stewardship in Agriculture (ICASA) one of the largest public-private partnerships focusing on improving antibiotic use (antibiotic stewardship) in animal agriculturecommits to investing in research to accelerate innovation and antibiotic stewardship across the livestock supply chain. Pfizer Inc. (New York, U.S.) One Drop, a non-profit foundation specializing in water, sanitation, and hygiene (WASH), commits to supporting WASH in healthcare facility initiatives in Haiti, Burkina Faso, Mali, and Malawi through co-financing and technical assistance. ALK supports the National Penicillin Allergy Day campaign and strives to see increased participation from healthcare providers and practices in 2019. The Kentucky Department for Public Health (KDPH) commits to addressing the threat of antibiotic resistance through improving detection of resistance threats and strengthening capacity to respond and contain threats quickly. Keep Antibiotics Working will work with all levels of U.S. government, livestock producers, supermarkets, restaurants, and other large purchasers of animal products. The platform will help eliminate the unnecessary use and overuse of antibiotics that contribute to the rise of antibiotic-resistant pathogens by providing the care team with information to inform diagnosis. Illinois Department of Public Health (Illinois, U.S.) ContraFect Corporation, a developer of biologic therapies, commits to developing new treatment options for life-threatening, antibiotic-resistant infectious diseases using direct lytic agents (DLAs) from its lysin and amurin product platforms. Activities include surveillance and lab testing for resistant organisms; optimizing infection prevention in all healthcare settings; encouraging appropriate communication of resistance threats to healthcare providers and facilities; promoting judicious use of antibiotics in all One Health settings; promoting appropriate use of vaccinations; and responding to and containing antibiotic-resistant threats. ASHP also offers a consulting service to assist hospitals and health systems with the development or enhancement of stewardship programs. We will continue to mine the data and share insights with CDC to support efforts to improve care. International Confederation of Midwives (Netherlands) Progress will be measured through an annual review of healthcare facilities provided with WASH facilities. These companies, employees, and partner organizations commit to advancing knowledge among clinicians, policymakers, and payers of the benefits of using innovative, biomarker-assisted sepsis treatment and antibiotic use to improve critical public health outcomes. The North Dakota Department of Healths (NDDoH) Healthcare-Associated Infection Program commits to expanding a certificate opportunity for pharmacists to participate in a self-study training to implement, evaluate, or modify antibiotic stewardship activities at the facilities they serve in their community. With more than 5,000 stores and clubs nationwide, Walmart US will ask animal protein suppliers to report antibiotic use throughout their supply chain and will conduct blockchain projects, which will provide greater transparency about antibiotic use on the farm and throughout the supply chain, starting with pork in 2018.
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